MR signal intensity in the bone marrow varies in healthy persons both on STIR/T2FS and T1-weighted sequences. Minor areas of increased subchondral signal on STIR/T2FS often occur in individuals above 30 years, but the extent is limited and deep and/or intense BME is rare, most frequently occurring anteriorly in the sacrum corresponding to the strain-related areas, doi:10.1002/art.42145.
On T1-weighted images there can be a patchy distribution of fat within the bone marrow with an increasing prevalence with increasing age and especially seen in a degenerative setting.
Erosion or erosion-like lesions may also occur as a normal finding, especially in middle aged and elderly persons. Besides, sclerosis, osteophytes and joint space alterations can occasionally be detected, but these features are best visualized by CT being detected with increasing frequency with age, doi:10.1016/S0009-9260(98)80316-4.